EndoFlip®
Impedance Planimetry
By measuring pressure, "distensibility” can be calculated using the formula cross sectional area/balloon pressure. This indicates how much a stoma or sphincter stretches when challenged by the balloon when it is inflated to a given pressure.
This "compliance-like" figure differs from compliance, calculated as volume/pressure, which is more appropriate to a closed volume, such as a pouch for example. See below for example.
Impedance monitoring will have broad applications for gastroenterologists as well as those performing anti-reflux procedures. Impedance monitoring removes the need for assumptions by showing the actual bolus transit.
Papers
| Title: | Esophagogastric Junction Distensibility After Fundoplication Assessed with a Novel Functional Luminal Imaging Probe |
| Author(s): | Monika A. Kwiatek, Peter J. Kahrilas, Nathaniel J. Soper, William J. Bulsiewicz, Barry P. McMahon, Hans Gregersen and John E. Pandolfino |
| Ref: | J Gastrointest Surg DOI 10.1007/s11605-009-1086-1 |
| Title: | Do we really understand the role of the oesophagogastric junction in disease? |
| Author(s): | Barry P McMahon, Blair A Jobe, John E Pandolfino and Hans Gregersen |
| Ref: | World J Gastroenterol 2009 January 14; 15(2): 144-150 |
| Title: | Esophagogastric junction distensibility: a factor contributing to sphincter incompetence |
| Author(s): | John E Pandalfino, Guoxiang Shi, Jennifer Curry, Raymond J Joehl, James G Brasseur and Peter J Kahrilas |
| Ref: | Am J Physiol Gastrointest Liver Physiol 282: G1052–G1058, 2002; 10.1152/ajpgi.00279.2001. |
| Title: | Esophagogastric junction opening during relaxation distinguishes nonhernia reflux patients, hernia patients and normal subjects |
| Author(s): | John E Pandalfino, Guoxiang Shi, Brian Trueworthy and Peter J Kahrilas |
| Ref: | Gastroenterology 2003;125:1018–1024 |
| Title: | Functional oesophago-gastric junction imaging |
| Author(s): | Barry P McMahon, Asbjørn M Drewes and Hans Gregersen |
| Ref: | World J Gastroenterol 2006 May 14; 12(18): 2818-2824 |
| Title: | Increased esophagogastric junction distensibility in GERD patients assessed with the endoscopically placed functional luminal imaging probe - abstract |
| Author(s): | Monika A Kwiatek, Ikuo Hirano, Peter J Kahrilas, Barry McMahon and John E Pandolfino |
| Title: | Restoration of normal distensive characteristics of the esophagogastric junction after fundoplication |
| Author(s): | John E Pandolfino, Jennifer Curry, Guoxiang Shi, Raymond J. Joehl, James G. Brasseur and Peter J. Kahrilas |
| Ref: | Ann Surg 2005;242: 43–48 |
| Title: | The functional lumen imaging probe (FLIP) for evaluation of the esophagogastric junction |
| Author(s): | Barry P McMahon Jens B Frøkjær, Peter Kunwald, Donghua Liao, Peter Funch-Jensen, Asbjørn M. Drewes, and Hans Gregersen |
| Ref: | Am J Physiol Gastrointest Liver Physiol 292: G377–G384, 2007. |
| Title: | A new technique for evaluating sphincter function in visceral organs: application of the functional lumen imaging probe (FLIP) for the evaluation of the oesophago-gastric junction |
| Author(s): | Monika A. Kwiatek, Ikuo Hirano, Daniel Luger, Peter J. Kahrilas, Nirmala Gonsalves and John E. Pandolfino |
| Title: | The relationship between symptom response, esophageal eosinophilia and wall distensibility in eosinophilic esophagitis - A pilot study following proton pump inhibitor therapy |
| Author(s): | Monika A. Kwiatek, Ikuo Hirano, Daniel Luger, Peter J. Kahrilas1, Nirmala Gonsalves and John E. Pandolfino |
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